Capillary Electrophoresis - Mass Spectrometry (CE-MS) - download pdf or read online

By Gerhardus de Jong

ISBN-10: 3527339248

ISBN-13: 9783527339242

ISBN-10: 3527693807

ISBN-13: 9783527693801

ISBN-10: 3527693815

ISBN-13: 9783527693818

ISBN-10: 3527693823

ISBN-13: 9783527693825

ISBN-10: 3527693831

ISBN-13: 9783527693832

This monograph deals the reader a whole evaluation on either ideas and functions of CE-MS. beginning with an introductory bankruptcy on detection in CE, additionally similar and extra really expert strategies comparable to electrophoretic and chromatographic preconcentration are mentioned. a unique emphasis is wear CE-MS interfaces, that are defined intimately. In a separate bankruptcy, cognizance is paid to sheath-liquid interfacing. The advancements and probabilities of microchip CE-MS also are defined. purposes to all appropriate components are mentioned in special chapters, each one written through specialists within the respective fields.
in addition to functions in pharmaceutical research and bioanalysis, fresh implementations in nutrients technological know-how, forensic research, research of intact proteins, metabolomics and proteomics are highlighted. MS is a wonderfully applicable detection approach for CE, as effective separation is coupled to delicate and choice detection. furthermore, MS delivers constitution info at the separated compounds. CE-MS has now been built right into a powerful hyphenated method complementary to LC-MS. This monograph is an exact resource of information for everybody facing and attracted to CE-MS

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Additional resources for Capillary Electrophoresis - Mass Spectrometry (CE-MS) Principles and Applications

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63. 64. 65. 66. 67. 68. using a porous tip. Anal. , 79, 4241–4246. , and Schappler, J. (2012) Evaluation of a sheathless nanospray interface based on a porous tip sprayer for CE-ESI-MS coupling. Electrophoresis, 33, 552–562. H. (2013) Comparing and combining CE-ESI-MS and nano-LCESI-MS for the characterization of post-translationally modified histones. Mol. Cell. Proteomics, 12, 2640–2656. A. (2010) High capacity capillary electrophoresis–electrospray ionization mass spectrometry: Coupling a porous sheathless interface with transientisotachophoresis.

2011) Flow-through microvial facilitating interface of capillary isoelectric focusing and electrospray ionization mass spectrometry. Anal. , 83, 8748–8755. 39. Y. 40. 41. 42. 43. 44. 45. 46. (2012) Capillary electrophoresis mass spectrometry for the characterization of O-acetylated N-glycans from fish serum. Anal. , 84, 8756–8762. Y. (2014) Simple capillary electrophoresis–mass spectrometry method for complex glycan analysis using a flow-through microvial interface. Anal. , 86, 6479–6486. Y. (2011) A promising capillary electrophoresis–electrospray ionization–mass spectrometry method for carbohydrate analysis.

5 Conclusion 31 32 2 Electrospray Ionization Interface Development for Capillary Electrophoresis–Mass Spectrometry Abbreviations BGE CA CE-MS CI cIEF cITP CRM CZE EI EOF ESI IEM LOD MALDI MRM nL pI SRM S/N background electrolyte carrier ampholyte capillary electrophoresis–mass spectrometry chemical ionization capillary isoelectric focusing capillary isotachophoresis charge residue model capillary zone electrophoresis electron ionization electroosmotic flow electrospray ionization ion evaporation model limit of detection matrix-assisted laser desorption/ionization multiple reaction monitoring nanoliter isoelectric point selected reaction monitoring signal-to-noise ratio Acknowledgments The authors would like to thank E.

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Capillary Electrophoresis - Mass Spectrometry (CE-MS) Principles and Applications by Gerhardus de Jong


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