Download e-book for kindle: Bioreactor Systems for Tissue Engineering by D. Wendt, S. A. Riboldi, M. Cioffi, I. Martin (auth.), Dr.

By D. Wendt, S. A. Riboldi, M. Cioffi, I. Martin (auth.), Dr. Cornelia Kasper, Prof. Martijn van Griensven, Dr. Ralf Pörtner (eds.)

ISBN-10: 3540693564

ISBN-13: 9783540693567

The editors of this particular quantity might first wish to thank all authors for his or her first-class contributions. we'd additionally wish to thank Prof. Dr. Thomas Scheper, Dr. Marion Hertel and Ulrike Kreusel for offering the chance to compose this quantity and Springer for organizational and technical help. Tissue engineering represents one of many significant rising fields in smooth b- know-how; it combines various topics starting from organic and fabric sciences to engineering and medical disciplines. the purpose of tissue engineering is the advance of healing ways to replacement diseased organs or tissues or increase their functionality. consequently, 3 dimensional biocompatible fabrics are seeded with cells and cultivated in appropriate structures to generate practical tissues. many various elements play a task within the formation of 3D tissue constructions. within the first position the resource of the used cells is of the maximum value. to avoid tissue rejection or immune reaction, preferentially autologous cells at the moment are used. specifically, stem cells from assorted resources are gaining unparalleled value as they are often differentiated into various tissues by utilizing specific media and supplementations. within the box of biomaterials, quite a few scaffold fabrics exist already yet new composites also are being constructed in line with polymeric, common or xenogenic assets. in addition, an important factor in tissue en- neering is the formation of tissues less than good outlined, managed and reprod- ible stipulations. hence, a considerable variety of new bioreactors were developed.

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Additional resources for Bioreactor Systems for Tissue Engineering

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2 Mechanical Failure Within the Tissue ...................................................................... 3 Mechanical Failure at the Tissue-to-Tissue Interfaces.............................................. 4 Metabolic Failure ...................................................................................................... 5 Cellular Necrosis and Cell Death.............................................................................. 6 Toxic Contamination.................................................................................................

2002) Cardiovascular tissue engineering: a new laminar flow chamber for in vitro improvement of mechanical tissue properties. ASAIO J 48 (1):8–11 11. Mironov V et al. (2006) Cardiovascular tissue engineering I. Perfusion bioreactors: a review. J Long Term Eff Med Implants 16(2):111–130 12. Dvir T et al. (2006) A novel perfusion bioreactor providing a homogenous milieu for tissue regeneration. Tissue Eng 12(10):2843–2852 13. Chen HC, Hu YC (2006) Bioreactors for tissue engineering. Biotechnol Lett 28(18):1415–1423 14.

Although these devices are promising in terms of development of functional biological vascular grafts [1, 2, 4, 6], they still present several drawbacks regarding biomechanical properties, the anatomical sample geometry and a restricted sample capacity. A couple of bioreactors have been designed to evaluate systematically the intrinsic effect of specific mechanical and biochemical stimuli on engineered tissues [8–10]. These devices offer a user-defined mode of mechanical stimulation, provide a sufficient sample capacity for statistically significant comparisons at multiple time points and accommodate basic sample geometry (Fig.

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Bioreactor Systems for Tissue Engineering by D. Wendt, S. A. Riboldi, M. Cioffi, I. Martin (auth.), Dr. Cornelia Kasper, Prof. Martijn van Griensven, Dr. Ralf Pörtner (eds.)


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