By Jeffrey H. Miner
Basement Membranes makes a speciality of really good extracellular matrices that supply the scaffolds used and required through cells to prepare themselves into tissues and organs. As basement membranes were proven to be faulty in different genetic and bought ailments and to give a contribution to the microenvironment of either tumor cells and stem cells, this publication offers a view of particular basement membrane elements and their roles in improvement and sickness, all written and commented on in chapters written via leaders within the basement membrane field.
- Written by way of major specialists within the basement membrane field
- Contains unique fabric, either textual and illustrative, that are supposed to turn into a really correct reference material
- Presents fabric in a really accomplished manner
- Ideal for either researchers within the box and normal readers who will locate appropriate and updated details
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Extra info for Basement membranes
Tarumi, Y. , Zhong, Y. , Proctor, T. , et al. (2005). Coordinate control of axon defasciculation and myelination by laminin-2 and -8. Journal of Cell Biology, 168, 655e666. Yurchenco, P. D. (2011). Basement membranes: cell scaffoldings and signaling platforms. Cold Spring Harbor Perspectives in Biology, 3, a004911. Yurchenco, P. , & Cheng, Y. S. (1993). Self-assembly and calcium-binding sites in laminin. A three-arm interaction model. Journal of Biological Chemistry, 268, 17286e17299. Yurchenco, P.
Type IV collagen “7s” tetramer formation: aspects of kinetics and thermodynamics. Annals of the New York Academy of Sciences, 460, 530e533. Yurchenco, P. , & Patton, B. L. (2009). Developmental and pathogenic mechanisms of basement membrane assembly. Current Pharmaceutical Design, 15, 1277e1294. Yurchenco, P. , Tsilibary, E. , Charonis, A. , & Furthmayr, H. (1985). Laminin polymerization in vitro. Evidence for a two-step assembly with domain speciﬁcity. Journal of Biological Chemistry, 260, 7636e7644.
2012). , 2009; Yurchenco, Cheng, Campbell, & Li, 2004). Patients with the milder limbegirdle type of dystrophy that presents with symptoms after a year of age generally exhibit only reduced or nearnormal expression of the laminin-a2 as determined from immunostaining of muscle biopsies (Figure 4). These patients can still develop the associated neurological problems seen in the more common cases of MDC1A. , 2011). The selective N-terminal epitope loss suggests selective degradation of N-terminal domain(s) from the LN mutation, while the reduction in C-terminal epitope suggests reduced assembly of a secreted 18 Peter D.
Basement membranes by Jeffrey H. Miner