Download PDF by Eliana Scemes, David C. Spray: Astrocytes : Wiring the Brain

By Eliana Scemes, David C. Spray

ISBN-10: 1439825858

ISBN-13: 9781439825853

Astrocytes play varied roles in significant frightened procedure (CNS) functionality and disorder, and the connections that the astrocyte makes with different cells of the mind are crucial for quite a few very important neural projects. Bringing jointly contributions from foreign specialists on the best in their box, Astrocytes: Wiring the mind emphasizes mobile connections and surveys the most up-tp-date findings on astrocyte Read more...

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2002). Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. J Neurosci 22: 183–192. Butt AM, Kalsi A. (2006). 1 in glial functions. J Cell Mol Med 10: 33–44. Cahoy JD, Emery B, Kaushal A, Foo LC, Zamanian JL, Christopherson KS, Xing Y, Lubischer JL, Krieg PA, Krupenko SA, Thompson WJ, Barres BA. (2008). A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J Neurosci 28: 264–278. Christianson GE.

A) GFAP immunolabeling of astrocytes. Individual astrocytes appear somewhat star shaped and are uniformly distributed, with little overlap with neighboring astrocytes. Astrocytic processes to blood vessels differ from other processes by being straight, unbranched, and of wider diameter (red arrowheads). The surfaces of large- to medium-size vessels were densely covered by GFAP+ astrocytic endfeet. Inset, an astrocyte with two vascular processes. (B) Double immunolabeling for AQP-4 (red) and GFAP (green).

2009). Possibly, there are different effects at different synapses, which will then take forever to describe. The basic implication is that PSAPs can act as boosters or dampers at individual synapses. Whether this also becomes a permanent aspect of any neuronal circuit is yet to be determined. 5 CONCLUSIONS So what is the most instructive way to view astrocyte functions to guide future studies? My view is obviously that they have support functions that are simpler to understand, and which themselves are better supported by the data, a little of which has 20 Harold K.

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